Melanie Schwenk, Doktorandin
Cornelia Hartig, Doktorandin
Martin Weilbächer, Doktorand
Philipp Hölter, MTA

Labor 147

Tel.: 06131-17-8147

• Molekulare Charakterisierung von T-Zellen

• Entwicklung T-Zell-modulierender Reagenzien

CD4-mediated regulatory T-cell activation inhibits the development of disease in a humanized mouse model of allergic airway disease.
Martin H, Reuter S, Dehzad N, Heinz A, Bellinghausen I, Saloga J, Haasler I, Korn S, Jonuleit H, Buhl R, Becker C, Taube C.
J Allergy Clin Immunol. 2011 Nov 10.

Lysozyme M-positive monocytes mediate angiotensin II-induced arterial hypertension and vascular dysfunction.
Wenzel P, Knorr M, Kossmann S, Stratmann J, Hausding M, Schuhmacher S, Karbach SH, Schwenk M, Yogev N, Schulz E, Oelze M, Grabbe S, Jonuleit H, Becker C, Daiber A, Waisman A, Münzel T.
Circulation. 2011 Sep 20;124(12):1370-81.

 Large scale preparation of human MHC class II+ integrin beta(1)+ Tregs.
Bonnin B, Correll A, Swiatek-de Lange M, Lenter M, Schneider FJ, Wijdenes J, Jonuleit H, Becker C.
J Immunol Methods. 2010 Aug 31;360(1-2):96-102.

Increased regulatory T-cell frequencies in patients with advanced melanoma correlate with a generally impaired T-cell responsiveness and are restored after dendritic cell-based vaccination.
Correll A, Tuettenberg A, Becker C, Jonuleit H.
Exp Dermatol. 2010 Aug;19(8):e213-21.

Generation of monoclonal antibodies against human regulatory T cells.
Becker C, Hoschützky H, Rist W, Lenter M, Schneider FJ, Jonuleit H.
J Immunol Methods. 2010 Feb 28;353(1-2):62-70.

Protection from graft-versus-host disease by HIV-1 envelope protein gp120-mediated activation of human CD4+CD25+ regulatory T cells.
Becker C, Taube C, Bopp T, Becker C, Michel K, Kubach J, Reuter S, Dehzad N, Neurath MF, Reifenberg K, Schneider FJ, Schmitt E, Jonuleit H.
Blood. 2009 Aug 6;114(6):1263-9.

Cyclic adenosine monophosphate is a key component of regulatory T cell-mediated suppression.
Bopp T, Becker C, Klein M, Klein-Hessling S, Palmetshofer A, Serfling E, Heib V, Becker M, Kubach J, Schmitt S, Stoll S, Schild H, Staege MS, Stassen M, Jonuleit H, Schmitt E.
J Exp Med. 2007 Jun 11;204(6):1303-10.

Human CD4+CD25+ regulatory T cells: proteome analysis identifies galectin-10 as a novel marker essential for their anergy and suppressive function.
Kubach J, Lutter P, Bopp T, Stoll S, Becker C, Huter E, Richter C, Weingarten P, Warger T, Knop J, Müllner S, Wijdenes J, Schild H, Schmitt E, Jonuleit H.
Blood. 2007 Sep 1;110(5):1550-8.

CD4-mediated functional activation of human CD4+CD25+ regulatory T cells.
Becker C, Kubach J, Wijdenes J, Knop J, Jonuleit H.
Eur J Immunol. 2007 May;37(5):1217-23.

Targeting of antigens to activated dendritic cells in vivo cures metastatic melanoma in mice.
Mahnke K, Qian Y, Fondel S, Brueck J, Becker C, Enk AH.
Cancer Res. 2005 Aug 1;65(15):7007-12.

CD8(+) T cells armed with retrovirally transduced IFN-gamma.
Becker C, Lienenklaus S, Jablonska J, Bauer H, Weiss S.
J Mol Med (Berl). 2007 Jan;85(1):63-73.

Adoptive tumor therapy with T lymphocytes enriched through an IFN-gamma capture assay.
Becker C, Pohla H, Frankenberger B, Schüler T, Assenmacher M, Schendel DJ, Blankenstein T.
Nat Med. 2001 Oct;7(10):1159-62